From Molecules to Molecular Surfaces: Organic Electrochemistry as a Tool for SynthesisSpeaker: Kevin Moeller, PhD, Professor, Department of Chemistry, Washington University in St. Louis Location: 402 N Blackford St. Indianapolis, IN 46202 LD 326T
Host: Ge (GIOSS)
Organic electrochemistry is a powerful tool for conducting a wide variety of oxidation and reduction reactions. It allows for the generation of highly reactive intermediates, the initiation of new umpolung reactions, the confinement of chemical reactions to specific sites on microelectrodes arrays, and the recycling of a wide variety of chemical reagents in a manner that is both atom and energy economical. Each of these reactions can be conducted with a constant current electrolysis. In a constant current electrolysis, the working potential at the electrode automatically adjusts to that of the substrate or catalyst in solution. The result is that reactions are simple to conduct and do not require specialized equipment. However, many synthetic chemists still hesitate to adopt the electrochemical methods. One of the keys to this hesitation is an unfamiliarity with electrochemistry and how to think about the reaction. With this in mind, the talk to be presented will use several synthetic examples as backdrops to highlight the key mechanistic features that govern electrochemical reactions. The goal will be to provide the insight needed for an organic chemist to take full advantage of electrochemistry as a synthetic tool.
For a key review please see : Moeller, K. D. Chem. Rev. 2018, ASAP.