minus plus magnify speech newspaper atomic biology chemistry computer-science earth-science forensic-services globe info math matrix molecule neuroscience pencil physics pin psychology email share atsign clock double-left-chevron double-right-chevron envelope fax phone tumblr googleplus pinterest twitter facebook feed linkedin youtube flickr instagram

Host: Laulhe

​Two recently developed Pd-catalyzed alkene difunctionalization reactions will be described. The first involves the coupling of alkenes bearing pendant aryl/alkenyl triflate electrophiles with nitrogen-, oxygen-, or carbon-centered electrophiles to afford carbocyclic product. The second involves the coupling of N-allylureas or N-allylguanidines with  O-acylated hydroxylamines, which act as nitrogen centered electrophiles, to afford heterocyclic alkene diamination products. Details of the development, stereocontrol, and reaction mechanisms of these transformations will be discussed.