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Use of Self-Assembled DNA Nanostructures to Control Arrangement of Single-Wall Carbon Nanotubes

Speaker: Kent Shilts, PhD Candidate, Department of Chemistry & Chemical Biology, IUPUI Location: 402 N Blackford St. Indianapolis, IN 46202 LD 010

Next generation transistors will require breakthroughs in materials science to allow smaller, more efficient devices to be fabricated. Single-wall carbon nanotubes (SWCNTs) are isomers of carbon with desirable properties, such as superior electron transport, for application as a semiconductor material to engineer nanoelectronics beyond the physical capability of current materials and techniques. One of the challenges with using SWCNTs in a device is the necessity to control the orientation and location of each SWCNT. Naturally, SWCNTs are deposited as clumped and bundled arrangements, therefore techniques to control the orientation and location of SWCNTs would be central to fabricating SWCNT transistors. Seeman and coworkers have recently shown that 2D nanostructures composed of DNA can position and orient SWCNTs.1  These 2D nanostructures were prepared by utilizing DNA origami techniques to fold a long single-stranded DNA (ssDNA) into a predetermined 2D shape with short staple strands of DNA that form stable crossover junctions with the ssDNA. Site-specific functionality of the SWCNT employed chemical functional groups, in this case SWCNTs were end functionalized with carboxylic groups and solubilized with DNA constructs possessing a terminal amine group. After synthesizing DNA end-labeled SWCNTs, these hybrid molecules were added to DNA origami constructs with complementary ssDNA, thereby a location specific bond was achieved. Orientation of the DNA end-labeled SWCNTs was controlled through noncovalent interactions between ssDNA rich areas of the DNA origami construct and the sidewall of a SWCNT. The capability to position and orient matter on the length scale of SWCNTs using DNA is a promising method for commercial scale-up of electronic and photonic devices made from SWCNTs.

1.         Pei, H.; Sha, R.; Wang, X.; Zheng, M.; Fan, C.; Canary, J. W.; Seeman, N. C., Organizing End-Site-Specific SWCNTs in Specific Loci Using DNA. Journal of the American Chemical Society 2019, 141 (30), 11923-11928.