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Developing the Crop Protection Attributes of a Natural Product

Speaker: Kevin Meyer, Principal Research Scientist, Crop Protection R&D, Dow AgroSciences Location: 402 N. Blackford St., Indianapolis, IN 46202 LD 010

Host: McLeish

Natural products, like UK-2A, have historically been rich sources for agricultural research due to their unique structures and novel modes of action. However, when used unmodified, they often lack the attributes needed to deliver robust field activity. Conversion of UK-2A to fenpicoxamid (InatreqTM active) produced a new active ingredient that delivers market leading control of economically important plant diseases. Further modifications to UK-2A led to molecules with improved plant stability and systemicity, opening up possibilities for new broad spectrum molecules with utility in a variety of crops. The strategies and methods used to investigate the potential of this class of chemistry will be presented and discussed.